Years have come and gone, but Avast! has never let me down. I remember it once saved my ass because it had that feature that let it scan for viruses before loading Windows if I recall correctly.
I have used lots of different antiviruses on different computers, both my own and on friends/family computers I "managed".
Used Avira on this one for a year (free one year subscription as a bonus from supplier) and it was useless most of the time, never even suspected most hacks of being "shady".
AVG used to be okay-ish, same as Kaspersky, Norton and what was that other N-thing? Nod32, is that a thing? That was useless too.
On the other hand, as a hacker (read "game hack user") it`s easier to have a somewhat useless antivirus, since it doesnt give so much trouble using hacks. Less exceptions to add, you know
EDIT: Just remembered that Dr.Web CureIt! has saved my lazy ass a couple of times when I let something into my beloved computer.